Gestational growth trajectories derived from a dynamic fetal–placental scaling law

Fetal trajectories characterizing growth rates in utero have relied primarily on goodness of fit rather than mechanistic properties exhibited in utero. Here, we use a validated fetal–placental allometric scaling law and a first principles differential equations model of placental volume growth to generate biologically meaningful fetal–placental growth curves. The growth curves form the foundation for understanding healthy versus at-risk fetal growth and for identifying the timing of key events in utero.

Keywords

Differential equation, Logistic growth model, Nonlinear regression, Fetal growth curves, Placenta, Placenta volume

Citation

Baller et al., “Gestational Growth Trajectories Derived from a Dynamic Fetal–Placental Scaling Law.”