Progress in the development of olfactory-based bioelectronic chemosensors
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Authors
Cave, John W.
Wickiser, John K.
Mitropoulos, Alexander
Issue Date
2019
Type
journal-article
Language
Keywords
Bioelectronic nose , Biosensor , Chemosensor , Odorant binding protein , Odorant receptor , Olfaction
Alternative Title
Abstract
Artificial chemosensory devices have a wide range of applications in industry, security, and medicine. The development of these devices has been inspired by the speed, sensitivity, and selectivity by which the olfactory system in animals can probe the chemical nature of the environment. In this review, we examine how molecular and cellular components of natural olfactory systems have been incorporated into artificial chemosensors, or bioelectronic sensors. We focus on the biological material that has been combined with signal transduction systems to develop artificial chemosensory devices. The strengths and limitations of different biological chemosensory material at the heart of these devices, as well as the reported overall effectiveness of the different bioelectronic sensor designs, is examined. This review also discusses future directions and challenges for continuing to advance development of bioelectronic sensors.
Description
Citation
Cave JW, Wickiser JK, Mitropoulos AN. Progress in the development of olfactory-based bioelectronic chemosensors. Biosens Bioelectron. 2019 Jan 1;123:211-222. doi: 10.1016/j.bios.2018.08.063. Epub 2018 Aug 27. PMID: 30201333.
Publisher
Biosensors and Bioelectronics
License
Journal
Volume
Issue
PubMed ID
ISSN
0956-5663